Advanced intestinal gut health feed additive for poultry, swine & calves

InteStim stands out because it is a unique combination of phytogenics with postbiotics in a synergistic, scientifically backed concept that delivers broad intestinal protection across pathogen types and animal species, while optimizing gut function and integrity.

Yes, InteStim is thermostable. All ingredients withstand high temperatures, ensuring optimal concentrations of active ingredients after the pelleting process.

Yes. InteStim provides a non-antibiotic pathway to manage pathogen pressure by using phytoactives to disrupt bacterial membranes and postbiotics to bolster the intestinal microbiome. InteStim is specifically formulated for AGP-free (Antibiotic Growth Promoter) environments. It addresses the “performance gap” often seen when AGPs are removed by providing alternative mechanisms for pathogen control and anti-inflammatory support.

Absolutely. Young animals often see the greatest ROI because their gastrointestinal tracts are sterile at birth and highly plastic. InteStim supports the “Microbial Programming” phase by helping beneficial pioneer colonizers establish themselves before pathogens can. InteStim also promotes intestinal morphology and immune development. This early intervention “primes” the gut for lifelong resilience.

The gut is the largest immune organ in the body. Up to 70% of the immune system is located in the Gut-Associated Lymphoid Tissue (GALT). Poor gut health leads to “nutrient hijacking,” where the animal consumes protein and energy to fight subclinical inflammation rather than for growth. Furthermore, a compromised gut barrier allows endotoxins (LPS) to enter the bloodstream, triggering a systemic inflammatory response that severely depresses appetite and weight gain.

Strengthening intestinal resilience is therefore a key strategy for:

– improving feed efficiency
– reducing disease pressure
– supporting sustainable production

InteStim is a multi-species solution designed for monogastric animals (poultry and swine) and pre-ruminants (calves). It is particularly effective during high-stress physiological windows, such as weaning in piglets, the starter phase in broilers, and the transition to solid feed in calves, where the enteric nervous system and microbiome are most vulnerable.

InteStim serves as a cornerstone in Antibiotic-Free (ABF) and Raised Without Antibiotics (RWA) programs. While it is not a direct “drop-in” pharmaceutical replacement for treating clinical infections, it functions as a prophylactic strategy. By balancing the intestinal microbiome, it prevents the dysbiosis that typically necessitates antibiotic intervention.

InteStim is particularly effective in periods of intestinal stress:

1. Poultry
   – Coccidiosis pressure
   – Heat stress
   – Feed transitions
   – Performance variability
2. Swine
   – Weaning stress
   – Post‑weaning diarrhea
   – Neonatal diarrhea
   – Dysbiosis challenges
   – High pathogen pressure
3. Calves
   – Early-life digestive instability
   – Scours risk
   – Stress from grouping or transport

Yes. InteStim is engineered to optimize Feed Conversion Ratio (FCR) and Average Daily Gain (ADG). By supporting gut integrity and microbiome balance, nutrient digestibility, and by reducing pathogen pressure and inflammation, InteStim helps animals absorb nutrients more efficiently, which translates into better growth performance and improved FCR (especially under gut-challenge conditions).

Preventing enteric issues in poultry requires a holistic approach, involving nutrition and management strategies:

– Start with biosecurity + litter/water hygiene: keep houses dry, manage wet litter fast, maintain drinking lines clean, and enforce strict cleaning and downtime between flocks.

– Optimize nutrition and gut function: use highly digestible raw materials, control anti-nutritional factors, balance amino acids, manage fat quality, and avoid abrupt feed changes.

– Support a stable microbiome: apply targeted gut-support additives (for example postbiotics, phytogenics, organic acids, and selected enzymes) based on the main challenge and age phase.

– Reduce pathogen pressure: vaccination where relevant, robust coccidiosis control, and early detection with routine monitoring (droppings, litter score, uniformity, mortality, lesion checks).

– Lower stress and immune suppression: maintain ventilation and temperature, prevent heat stress, avoid overcrowding, and ensure consistent access to feed and water.

Calf gut development is a race against time between birth and weaning. Support should focus on both anatomical growth and microbial colonization:

– Colostrum and transition milk first: deliver enough high-quality colostrum quickly, then use transition milk to drive early gut maturation and local immunity.

– Feed promoting rumen and intestinal development: consistent milk/milk replacer program, offer clean water from day 1, and introduce a palatable starter early to stimulate rumen papillae and gut enzyme activity.

– Protect the gut from pathogen entry: excellent hygiene for feeding equipment and housing, reduce exposure pressure, and use evidence-based scours prevention (including vaccination and monitoring where relevant).

– Support the intestinal microbiome and barrier function: consider targeted supplements in milk or feed (for example postbiotics, organic acids, and selected phytogenics) especially around stress moments.

– Minimize stress and inflammation: keep calves warm and dry, avoid overcrowding, manage weaning gradually, and maintain stable routines to prevent setbacks in intake and gut integrity.

Yes. InteStim can be used both in neonatal and post‑weaning phases to support gut integrity and intestinal microbial balance, helping animals stay more resilient to diarrhea risk, especially during those high-stress transitions,while it should be used as part of a broader hygiene, nutrition, and health program.

Microbiota balance, or eubiosis, is improved by stabilizing the gastrointestinal environment through a multi-factorial approach:

– Stable, well-balanced diets: consistent feeding times, adequate fiber structure, and avoiding sudden ration changes help prevent dysbiosis.

– High feed and water hygiene: limit mycotoxins, rancid fats, and microbial contamination, and keep water quality and drinker lines clean.

– Support fermentation and gut barrier function: use targeted tools like biotics, organic acids, and enzymes when they match the species, age, and challenge.

– Reduce disease pressure and inflammation: strong biosecurity, vaccination programs where relevant, and early control of enteric pathogens and parasites.

– Lower stressors: optimize stocking density, temperature, ventilation, transport handling, and weaning transitions, since stress reliably disrupts microbiota stability.