Nutrex is dedicated to offering and constantly innovating its unique range of top quality product solutions to help enhance animal health, animal well-being and increase performance in various stages of swine production.
Ear necrosis in pigs – A multifactorial problem.
Ear necrosis is a multifactorial problem. The potential causes of ear necrosis can be divided into infectious and non-infectious causes. Mycotoxins and endotoxins, which are often present together in production animals are risk factors contributing to the development of ear necrosis.
Mycotoxins – a force to be reckoned with!
Mycotoxin contamination in food and feed is a worldwide problem. Among hundreds of known mycotoxins, aflatoxins (AFs), ochratoxin A (OTA), fumonisins (FBs), zearalenone (ZEA) and trichothecenes (DON, T-2, HT-2) are considered the major mycotoxins in animal production. Mycotoxins are a force to be reckoned with as they cause significant economic losses due to their impact on animal performance.
Endotoxins are toxic compounds from bacterial origin. The most well-known endotoxins are lipopolysaccharides (LPS), which are part of the cell wall of Gram-negative bacteria. During normal bacterial division and lysis, LPS molecules are released from the bacterial outer membrane into the environment, such as the air, water, soil and gastrointestinal tract (GIT).
Endotoxins: Inducers of inflammation
Endotoxins are important inducers of inflammation. Inflammation is a costly affair diverting energy and nutrients meant for growth and production towards the immune system.
The synergistic effect of mycotoxins and endotoxins
Mycotoxins and endotoxins are both toxins that present a health risk to production animals, albeit of different origins. Mycotoxins and endotoxins are often present together in the gastrointestinal tract of production animals and cause severe economic losses. In addition, their adverse effect on the animals health and performance can be enhanced synergistically.