Swine gut integrity & health:
from digestion to disease prevention and performance

The benefits of a healthy intestinal tract extend beyond the gut – it drives resilience, growth, feed efficiency, and  farm profitability

The pigs’ gastrointestinal tract (GIT) or gut plays a crucial role in processing feed into absorbable nutrients that their body needs for maintenance and production.

Howerever, digestive disorders represent one of the most significant health challenges in modern pig production, causing substantial economic losses through increased mortality, reduced growth rates, and higher treatment costs.

As the industry moves away from routine antibiotic use, safeguarding gut integrity has become a priority. Effective strategies now focus on enhanced biosecurity, optimized nutrition, and targeted interventions that strengthen digestive function and resilience.

The pig’s digestive system

The porcine digestive system is specialized for omnivorous feeding, featuring:

  • A simple stomach
  • Well-developed large intestine (4-6 meters) for fiber fermentation
  • Small intestine (15-22 meters) for enzymatic digestion and nutrient absorption
  • A diverse gut microbiome dominated by Clostridiales, Bacteriodiales and Lactobacillales
  • Well-developed Peyer’s patches and other gut-associated lymphoid tissues reflecting the importance of the gut as an immunological organ
  • A particularly vulnerable gut during the weaning transition

The role of gut health in swine production

Gut integrity in pigs goes far beyond digestion; it is the foundation of overall health, growth, and profitability.

The gastrointestinal tract (GIT) or gut performs multiple critical functions. Beyond breaking down feed, it serves as the pig’s primary barrier against pathogens and toxins. The intestinal epithelium represents the largest interface with the external environment, acting as the first line of defense. When this barrier is compromised, a condition commonly known as “leaky gut“, pathogens and harmful metabolites can enter circulation, triggering inflammation and systemic health challenges.

An impaired gut not only activates the immune system but also diverts nutrients and energy away from growth and production. Chronic gut inflammation reduces lean tissue deposition, lowers feed efficiency, and negatively impacts average daily gain (ADG). Over time, these disruptions contribute to poor feed conversion ratios (FCR) and measurable economic losses.

Conversely, maintaining a healthy gut improves nutrient absorption, strengthens immune defenses, and optimizes growth performance. Proactive management of gut integrity is therefore essential, as it directly supports resilience, efficiency, and long-term profitability in swine production.

Signs of poor gut health

Recognizing poor gut health in pigs requires careful observation of
various behavioral and physical indicators.

Fig. Signs of poor gut health
Fig. Signs of poor gut health

⚠️ Watch for these key indicators:

– Diarrhea or loose feces

– Reduced feed intake and decreased growth

– Lethargy and behavioral changes

– Bloating and signs of abdominal pain

– Blood or mucus in feces

Causes of gut health disorders

The onset of gut disorders in pigs can have an infectious or non-infectious origin. The distinction between infectious and non-infectious causes often blurs, as
non-infectious factors frequently predispose animals to pathogen susceptibility by disrupting the gut’s protective mechanisms e.g. damaged gut integrity opens the door for pathogens and associated endotoxins.

Non-infectious causes of diarrhea

  • Nutritional factors such as sudden diet changes, excessive fermentable carbohydrates, inadequate fiber, or antinutritional factors in feed ingredients.
  • Feed contaminants e.g. mycotoxins
  • Management-related stressors e.g. weaning, transportation, climate, and overcrowding
  • Water quality issues

Infectious causes of diarrhea

  • Diverse range of pathogens
  • Age-related patterns

Common disorders by age group

A pig’s life is full of physiological and environmental challenges, with each stage presenting unique risks to gut health and overall performance.

Even before birth, nutrient availability and maternal health play a critical role in piglet development. After birth, piglets face additional pressures, including weaning stress, exposure to pathogens, and dietary transitions that can compromise gut integrity. As pigs grow into the finishing stage, continued exposure to pathogens and environmental stressors further tests their resilience.

Causative agents for intestinal disorders affecting specific age groups
Fig. Causative agents for intestinal disorders affecting specific age groups

A diverse range of pathogens can disrupt the gastrointestinal tract, typically following age-related patterns.

Piglets

Primarily affected by enterotoxigenic E. coli, Clostridiosis, rotavirus, and coccidiosis. These infections can be devastating, with some viral diseases like PED and TGEV causing up to 100% mortality in neonates.

Weaned pigs

Most vulnerable to E. coli, Salmonella, Lawsonia intracellularis, and Brachyspira species. The weaning transition creates ideal conditions for pathogens through multiple stressors that compromise gut function.

Sows

Commonly affected by Lawsonia intracellularis, Brachyspira, and viral pathogens like PEDV. Diarrhea in sows impacts not only the animal but also compromises milk production and litter performance.

Conclusion: the importance of gut health management in swine

The porcine gastrointestinal system is a complex ecosystem whose proper functioning directly impacts growth performance, feed efficiency, and overall herd health. With the global shift away from routine antibiotic use, producers must adopt a multifaceted approach to gut health that encompasses nutrition, biosecurity, environment, and targeted interventions.

By focusing on gut health, producers can improve feed efficiency, enhance growth, and ultimately boost profitability.

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