EndoBan® | Endotoxin reducer

EndoBan®
Endotoxin reducer

Available for

Reduces the threat of endotoxins to boost performance

EndoBan®

EndoBan is an innovative feed additive combining several strategies to reduce the leakage of endotoxins through the gastrointestinal barrier. EndoBan improves animal performance by preventing energy-consuming inflammatory responses.

Disarm the endotoxins

Endotoxins are toxins from bacterial origin. The most well-known endotoxins, lipopolysaccharides (LPS), are components of the cell wall of Gram-negative bacteria. LPS molecules are released into the environment when bacteria multiply or when their cell membranes rupture through bacterial lysis.

In healthy animals, the gut acts as a barrier to endotoxins entering the blood and is thus essential to prevent the translocation of endotoxins. However, several external factors (e.g. heat stress, mycotoxins, pathogens, feed transition) are known to increase gut permeability, promoting leakage of endotoxins.

Once endotoxins pass the intestinal barrier, they trigger an inflammatory response that will consume energy and nutrients ideally meant for growth and production. This will reduce animal performance and make them more susceptible to other stressors as well.

Extensive in vitro and in vivo research across multiple species has proven EndoBan’s ability to reduce the leakage of endotoxins and improve performance.

Use of EndoBan is highly recommended when gut health is compromised

Poultry

  • Use of antibiotics
  • During heat stress
  • Mycotoxin contamination in feed
  • Presence of pathogens
  • Use of high-fat diets
  • For hens housed in cage-free systems, which are affected more frequently by intestinal disorders
  • At the onset of lay
  • Presence of fatty liver

Swine

  • Use of antibiotics
  • During heat stress
  • Mycotoxin contamination in feed
  • Presence of pathogens
  • Use of high-fat diets
  • Transition from gestation to lactation feed
  • Around weaning

Cattle

  • Use of antibiotics
  • During heat stress
  • Mycotoxin contamination in feed
  • Presence of pathogens
  • Use of a diet high in rapidly fermentable carbohydrates (SARA)
  • Transition period
  • Around weaning
  • Presence of fatty liver

Aquaculture

  • Use of antibiotics
  • Poor water quality
  • Mycotoxin contamination in feed
  • Presence of pathogens
  • Dietary changes
  • High stocking density

EndoBan’s key distinguishing benefits

  • Improves feed efficiency and growth
  • Improves health
  • Limits leakage of endotoxins through GIT barrier
  • Prevents energy-consuming inflammatory responses

 

EndoBan’s key distinguishing properties

  • One product for all animal species
  • Highly stable
  • Safe to use from start to finish, in rearing and production
  • Can be used in antibiotic-free diets

Insights

Product availability and supported claims may vary by country, please contact us for more information.